Jimenez Group

Ralph Jimenez group

Sakpal

My research is focused on the single molecule-single photon imaging of NanoLuc-furimazine complex. In addition, I am working on the development of bright and photostable red fluorescent proteins. 

Fluorescent Proteins

Since the isolation of the first naturally fluorescing protein from jelly fish in the 1960s, fluorescent proteins (FPs) have become integral to a wide range of biological/medical applications, allowing visualization of biomolecules and processes in living cells and tissues to a much greater degree than was previously possible. Extensive molecular engineering of naturally occurring FPs has led to several families of recombinant proteins tailored to specific biophysical and imaging purposes.

Quantum Spectroscopy

Our group is actively engaged at the interface of quantum optics with physical chemistry. In this research, we manipulate the properties of light at the single photon or few photon level.  By employing “quantum engineered” light for spectroscopy, we aim to harness the remarkable quantum mechanical properties such as entanglement, superposition, and coherence in order to increase the sensitivity and information content of spectroscopy.