STROBE Seminar

Nanoscale Imaging: Soft X-ray STXM and Ptychography at the ALS

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Abstract: Advancements in materials research increasingly require visualization of structure, composition, and functionality at the nanometer scale. Soft X-ray Ptychography and Scanning Transmission X-ray Microscopy (STXM) are two complementary techniques that leverage the brightness and coherence of synchrotron radiation at the Advanced Light Source (ALS) to probe materials with high spatial resolution and enhanced chemical sensitivity.

Deep Learning to Overcome Physical Limits in CryoEM and CryoET

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Abstract: CryoEM and cryoET enable imaging of biological specimens frozen in vitreous ice, revealing 3D molecular or cellular structures at high resolution and in their native state. However, cryoET is limited by the “missing-wedge” problem due to restricted tilt angles, and cryoEM often suffers from preferred orientation, resulting in uneven sampling of angular views and leaving parts of Fourier space poorly covered.

The Things We Thought We Knew About Optics and Coatings

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Optics and coatings are often considered as commodity in the laser systems
across different applications. And yet, these are the main factors limiting
the efficiency, power, and lifetime of lasers and optical layouts. Moreover,
coating engineers, just like masters of dark magic, have their own language.
I will cover a variety of topics and questions, which will help to grow
awareness about the critical characteristics of optics. Answers to those
questions will also help to learn some of the language coating engineers

Electron and Photon Detection for Microscopies

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Seeing small things takes bright lights and great optics. But you still have to see something. This talk will discuss detectors for electron and X-ray microscopies: how they work, what are they challenges, and where are the opportunities. The competition is intense: the human eye has ~108 ‘pixels’ and a dynamic range of ~104 (and has a direct connection to a built-in neural processor). No camera today can match these specs (although we are getting close).