Ribosome ubiquitination and translation control during oxidative stress

Lab Website: https://sites.duke.edu/silvalab/

Synopsis: The main goal of the Silva lab is to understand ubiquitin pathways in response to the oxidative stress response pathway with the goal being to develop ubiquitin centered therapies to counter cancer cells. The lab uses molecular biology tools, protein biochemistry, proteomics, structural biology, and next generation sequencing to investigate ubiquitination in yeast cells.