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Research Highlights

Published: Fri, 07/21/2017 - 2:45pm

The Perkins group has made dramatic advances in the use of Atomic Force Microscopes (AFMs) to study large single biomolecules, such as proteins and nucleic acids (DNA, RNA), that are important for life. After previously improving AFM measurements of biomolecules by orders of magnitude for stability, sensitivity and time response, the Perkins group has now developed ways to make these precision biomechanical measurements up to 100 times faster than previously possible––obtaining useful information in hours to days rather than weeks to months. 

The Perkins group uses its precision AFM technology to measure the tiny forces and structural states involved in the folding and unfolding of individual molecules of proteins and nucleic acids in their native wet, warm biological environments. How proteins fold and unfold normally––and sometimes misfold are crucial questions to understanding normal physiology and many of the most widespread and devastating diseases, such as cancers, neurodegenerative diseases, and some heart diseases. The Perkins group had already used their AFM technology to reveal new details in...

Published: Nov 30, 2015

In the future, quantum microwave networks may handle quantum information transfer via optical...

Published: Nov 06, 2015

JILA’s cold molecule collaboration (Jin and Ye Groups, with theory support from the Rey Group)...

Published: Nov 02, 2015

The Regal and Rey groups have come up with a novel way to generate and propagate quantum...

Published: Oct 21, 2015

Scientists often use ultracold atoms to study the behavior of atoms and electrons in solids and...

Published: Oct 16, 2015

Fellow Phil Armitage and his collaborator Jake Simon of the Southwest Research Institute...

Published: Oct 16, 2015

The Perkins Group has demonstrated a 50-to-100 times improvement in the time resolution for...

Published: Oct 05, 2015

It took Eric Cornell three years to build JILA’s first Top Trap with his own two hands in the...

Published: Sep 21, 2015

The Kapteyn/Murnane group, with Visiting Fellow Charles Durfee, has figured out how to use...

Published: Aug 19, 2015

Graduate student Brian Lester of the Regal group has taken an important step toward building...

Published: Aug 14, 2015

Ever wondered how magnetic pressure alone might be able to maintain the structure of an...

Published: Aug 10, 2015

Compact and transportable optical lattices are coming soon to a laboratory near you, thanks to...

Published: Aug 06, 2015

When an ordinary star like our Sun wanders very close to a supermassive black hole, it’s very...

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