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News & Highlights

Research Highlights

Published: Fri, 07/21/2017 - 2:45pm

The Perkins group has made dramatic advances in the use of Atomic Force Microscopes (AFMs) to study large single biomolecules, such as proteins and nucleic acids (DNA, RNA), that are important for life. After previously improving AFM measurements of biomolecules by orders of magnitude for stability, sensitivity and time response, the Perkins group has now developed ways to make these precision biomechanical measurements up to 100 times faster than previously possible––obtaining useful information in hours to days rather than weeks to months. 

The Perkins group uses its precision AFM technology to measure the tiny forces and structural states involved in the folding and unfolding of individual molecules of proteins and nucleic acids in their native wet, warm biological environments. How proteins fold and unfold normally––and sometimes misfold are crucial questions to understanding normal physiology and many of the most widespread and devastating diseases, such as cancers, neurodegenerative diseases, and some heart diseases. The Perkins group had already used their AFM technology to reveal new details in...

Published: Jul 21, 2016

The Raschke group has created an ultrafast optical nanoscope based on a unique way of “nano”...

Published: Jul 20, 2016

Bob Peterson and his colleagues in the Lehnert-Regal lab recently set out to try something that...

Published: Jun 28, 2016

Fellow Judah Levine recently presented a discussion of our understanding of time from antiquity...

Published: Jun 02, 2016

The Kapteyn/Murnane group has measured how long it takes an electron born into an excited state...

Published: May 04, 2016

The Ye group just solved a major problem for using...

Published: Apr 21, 2016

Move over, single-atom laser cooling! The Holland theory group has just come up with a stunning...

Published: Apr 20, 2016

The old JILA molecule factory (built in 2002) produced the world’s first ultracold polar...

Published: Mar 31, 2016

The Ye and Rey groups have discovered the strange rules of quantum baseball in which strontium (...

Published: Feb 10, 2016

Cong Chen and his colleagues in the Kapteyn/Murnane group have generated one of the most complex...

Published: Jan 28, 2016

The Rey and Ye groups are in the midst of an extended collaboration on using the Ye group’s...

Published: Dec 08, 2015

In 2008, Fellow Jeff Linsky and his colleague Seth Redfield of Wesleyan University used spectral...

Published: Dec 03, 2015

Imagine laser-like x-ray beams that can “see” through materials––all the way into the heart of...

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